Have you ever wondered how a single cell transforms into a complete multicellular organism? Or how a single cell gives rise to all sorts of functional cells, including nerve and cardiac cells? Well, Developmental biology is what concerns with the study of such intriguing questions, i.e., how living organisms, including plants and animals, grow and develop from single cells to an adult organism, where development continues even after the birth. The students studying developmental biology are required to be significantly determined and eager to learn the intricate processes giving rise to the development of various organisms. 

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What is Developmental Biology?

Having an idea about what we are getting ourselves into can help us comprehend and encounter it in a better way, so let's first discuss some basic concepts of developmental biology. We all start our lives as a single cell, the newly fertilized symmetrical cell called the zygote, from which a baby forms, which is by no means symmetrical like the zygote. How do we get here? Well, this is what developmental biology is all about. The central questions on developmental biology explain what can one learn in a course of this discipline. 

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  1. Cellular differentiation: We understand that via the process of mitosis, cells into two cells, and so on, but at one point they transform into different kinds of cells, which can not be a result of simple multiplication, for instance, a brain cell and a cardiac muscle cell. Cellular differentiation is the process that is responsible for the formation of the various kinds of cells and their lineages. 

  2. Morphogenesis: Merely becoming different kinds of cells isn’t enough, isn’t it? Well, of course, the cells have to be organised in a particular shape to sustain function, for example, muscle cells have to be organised into a muscle fibre to be of any use in the living organisms. This shape formation or organisation is the second main question, i.e., morphogenesis. 

  3. Growth: Once the organisation has taken place, an organism needs to grow as well, which cannot simply be a result of the expansion of cells. Instead, it has to be a controlled growth proportional to the overall body. How this growth is highly regulated and achieved is also studied under developmental biology.

  4. Reproduction: Another central question in developmental biology concerns with how organisms reproduce and how they generate the same kind in the next generation. 

  5. Evolution: How does developmental biology support evolution? Well, an adaptation or modification is possible only within the constraints of the current body plan, i.e., by the variations allowed by the development at a given generation. In that sense, evolution and developmental biology are intimately connected and hence, evolution can only happen to the extent variations and development can be accommodated. 

  6. Environmental Integration: Life doesn’t happen in isolation, does it? So, how does all of this integrate into the environment? What are the environmental influences? How does that affect the development of an organism? These are also some of the questions that developmental biologists are concerned with.

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