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Stereochemistry is one of the subdisciplines of chemistry which is dedicated to the study of spatial arrangements of atoms which is responsible for the formation of the structures of molecules and their modifications and manipulations. It is commonly known as 3D chemistry as the word ‘stereo’ means three-dimensionality.
In the naming of enantiomers of the chiral compounds, the ‘left hand’ and the ‘right hand’ nomenclature is used. And, the labeling of stereocenters is done as ‘R’ and ‘S’. In case the arrow points in the clockwise direction, ‘S’ is considered to be the stereocenter’s configuration.
It was in the year 1848 when in Paris at the Ecole Normale, a set of observations were made by Louis Pasteur led to the making of the proposal which founded the base of stereochemistry. Molecular asymmetry is used to study the organic solution’s optical activity which in turn is responsible for producing mirror-image structures that are non-superimposable.
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